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NOVELARA × GRAPE KING BIO
ErinaPrime is pure Lion’s Mane mycelium with 0.5% or 1% erinacine A, produced through submerged fermentation. We are proud to partner with Grape King Bio, building on their extensive work with erinacine A-enriched mycelium, including multiple published human studies.
THE RIGHT PART OF THE ORGANISM
Lion’s Mane fruiting body and mycelium are two parts of the same fungus, but they do not contain the same compounds.
Erinacine A is associated with cultured Lion’s Mane mycelium. It is not a marker for fruiting-body extract. ErinaPrime uses liquid-cultured mycelium and does not contain cereal grain.
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No myceliated grain. The mycelial biomass is grown in liquid culture, separated from the fermentation medium, freeze-dried and milled.
GRAIN-FREE VS. MYCELIUM ON GRAIN
ErinaPrime is grain-free Lion’s Mane mycelium produced through submerged fermentation and standardized to erinacine A. Many mycelium-on-grain materials contain the residual grain substrate as part of the finished ingredient. That difference matters, and it becomes clear in HPTLC.
See the HPTLC comparisonERINAPRIME
MYCELIUM ON GRAIN
HPTLC IDENTITY COMPARISON
Use the slider to compare a top-selling myceliated-grain Lion’s Mane product with rice flour, then with authenticated H. erinaceus mycelium.
All three crops come from the same HPTLC plate and are shown at the same scale. Bands were not edited. This comparison addresses identity, not quantity.
THE GRAPE KING RESEARCH PROGRAM
Grape King Bio and academic collaborators have published research on erinacine A-enriched H. erinaceus mycelium since 2014, including randomized human studies.
The studies used Grape King’s erinacine A-enriched H. erinaceus mycelium. The 49-week study used 0.5% material. ErinaPrime is available at 0.5% and 1%. Results depend on the population, dose and study design and should not be treated as finished-product claims.
Randomized · double-blind · placebo-controlled
3.44 mg erinacine A per day
The erinacine A-enriched Lion’s Mane group improved on the adjusted cognitive ability score. The study also reported greater gut-microbiota diversity and found the intervention safe and well tolerated.
Read the studyPilot · randomized · double-blind · placebo-controlled
1,050 mg/day of 0.5% material · 5.25 mg erinacine A
In participants with mild Alzheimer’s disease, the paper reported a within-group improvement in MMSE and a between-group difference in IADL at week 49. It also reported contrast-sensitivity findings. This was a small pilot study.
Read the open-access studyRandomized · double-blind · placebo-controlled
2,000 mg mycelium per day
Among participants aged 65 and older with hearing impairment, the subgroup analysis found between-group differences in several high-frequency and speech measures, along with an NGF finding.
Read the studyRepeated-dose safety and genotoxicity studies on erinacine A-enriched mycelium
Amyloid pathology and neurogenesis research in an Alzheimer’s disease mouse model
BDNF-pathway and stress-model research on erinacine A-enriched mycelium
Aging and longevity work in Drosophila and aged mice
Age-related cognition and sleep-disruption studies in animal models
A randomized cognition study in healthy older adults and a pilot erinacine A distribution study in a pig model
Review Grape King Bio’s published-paper index and the individual papers before developing claims.
GRAPE KING BIO MANUFACTURING
Grape King Bio develops the culture, conducts research and manufactures the mycelium at commercial scale in Taiwan. Novelara distributes ErinaPrime in cooperation with Grape King Bio.
Selected H. erinaceus mycelium is maintained and expanded.
Mycelium grows in a controlled submerged system without cereal grain.
The mycelial biomass is separated, stabilized and milled.
Finished powder is released to either the 0.5% or 1% erinacine A specification.
FORMULATION OPTIONS
ErinaPrime is available at 5 mg/g and 10 mg/g erinacine A. The two specifications give formulators flexibility without changing the fungal material or production method.
TECHNICAL DOCUMENTATION
Prospective customers can request the specification, representative CoA, analytical methods, manufacturing flow, country-of-origin information and published bibliography.
SAMPLES · PRICING · TECHNICAL SUPPORT
Tell Novelara which specification you are evaluating and your target dose. We can provide samples, pricing, documentation and formulation support.
